Statin lowers cholesterol and protects against heart disease, but it may cause muscle pain, liver issues, and nutrient deficiencies, particularly of CoQ10, vitamin D, and vitamin K2. Here is a full article that could help you understand these side-effects of statin (1).
🚨 What Are Statins?
Statin is a prescription drug that lowers Low-density Lipoprotein (LDL), which is also described as “bad” cholesterol.
This medicine does this by blocking a liver enzyme involved in cholesterol production.
It is widely used to prevent heart attacks and strokes.
Common Statin Brands
Atorvastatin (Lipitor)
Simvastatin (Zocor)
Rosuvastatin (Crestor)
Pravastatin (Pravachol)
⚠️ Common Side Effects Of Statin
Many people tolerate statin well, but some may experience side effects.
Here are the most frequently reported:
1. Muscle Pain Or Weakness
This is the most common complaint.
Statin can feel like soreness, stiffness, or fatigue.
Also, it often affects legs or back muscles.
2. Liver Enzyme Elevation
Statins can mildly increase liver enzymes
Routine liver function tests may be required
Rarely leads to serious liver damage
3. Digestive Issues
Nausea, bloating, constipation, or diarrhea
Usually mild and temporary
4. Increased Blood Sugar Or Type-2 Diabetes Risk
Statin may slightly raise blood sugar levels and this makes it typically a greater concern in those already at risk for diabetes.
5. Cognitive Symptoms
Some users report memory loss or confusion.
Interestingly, these effects are reversible upon stopping the drug
6. Sleep Disturbance Or Dizziness
Insomnia, vivid dreams, or light-headedness in some cases
Now, before we talk about the nutrients that Statin depletes in your body, we want to highlight that there is a natural way of lowering cholesterol in the body.
Taking this option is what we recommend since it comes will little or no side effects.
If you will want to know this natural way of lowering cholesterol, here is another article to read.
Related Article Â
Natural Ways To Reduce Cholesterol, Most Effective Lifestyle Changes Backed By Science
Cholesterol build up in the arteries could eventually result in blockage.
🧬 Nutrients Depleted By Statins
Statins can interfere with your body’s nutrient levels, particularly in long-term use. Here’s what to watch for:
| Nutrient | Function in the Body | Statin Impact |
|---|---|---|
| Coenzyme Q10 (CoQ10) | Vital for energy production and heart health | Statins block its natural synthesis, leading to fatigue, muscle pain |
| Vitamin D | Supports bone strength and immune function | Statins may lower blood levels over time |
| Vitamin K2 | Helps prevent arterial calcification and aids clotting | Lower levels may increase vascular risk |
| Omega-3 Fatty Acids | Essential for heart and brain health | Levels may be indirectly affected, especially in low-fat diets |
| Selenium | Key antioxidant that supports thyroid and immunity | Some studies link long-term statin use with lowered selenium levels |
đź’Š Should You Supplement?
You may want to know if there are other things you could take to sustain the level of these nutrients that statin may deplete.
Here are evidence-based recommendations:
✅ CoQ10: Supplementation (100–200 mg daily) may reduce statin-related muscle pain
âś… Vitamin D: Get your blood levels checked. Supplement if needed
âś… Omega-3s: A fish oil supplement or more fatty fish can be beneficial
âś… Balanced Diet: Eat more leafy greens, nuts, seeds, fatty fish, and fermented foods
⚠️ Always consult your doctor before adding supplements—especially if you’re on multiple medications.
đź“Ś Final Thoughts On Side Effects of Statin
Statins are life-saving for many, but it’s essential to monitor side effects and nutrient depletion.
By staying informed and adjusting your nutrition or supplements, you can safely get the most out of your statin therapy.
The secret is in staying proactive, nourished and heart-smart.
🗂️ FAQs About Side Effects Of Statin
Q: Do statins cause muscle pain?
A: Yes, muscle soreness is one of the most common side effects of statins.
Q: Which nutrients do statins lower?
A: Statins may reduce CoQ10, vitamin D, vitamin K2, omega-3 fatty acids, and selenium.
Q: Can I take supplements with statins?
A: Yes, but always consult your doctor before starting any supplements.